RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-208a
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
NA
Target
NA
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
Mechanical stretch via transforming growth factor-beta1 activates microRNA208a to regulate endoglin expression in cultured rat cardiac myoblasts
Year
2013
Function
Cyclic mechanical stretch enhances miR208a expression in cultured rat cardiac myoblasts. The stretch-induced miR208a is mediated by TGF-beta. miR208a activates endoglin expression and may result in cardiac fibrosis.